Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation

• Principais autores: Jing-Bo Zhou (Autor), Dongyang Tang (Autor), Lin He (Autor), Shiqi Lin (Autor), Josh Haipeng Lei (Autor), Heng Sun (Autor), Xiaoling Xu (Autor), Chu-Xia Deng (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2023-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Drug combination therapy is a highly effective approach for enhancing the therapeutic efficacy of anti-cancer drugs and overcoming drug resistance. However, the innumerable possible drug combinations make it impractical to screen all synergistic drug pairs. Moreover, biological insights into synergi...