A chalcone derivative SBD-2 exerts anticancer effects in human colorectal cancer cells

• Main Authors: Bowen Zheng (Author), Wanjun Lin (Author), Na Zhang (Author), Xiaoming Huang (Author), Jingjing Du (Author), Yunfu Shen (Author), Junhe Chen (Author), Qianyu Lin (Author), Zhuya Yang (Author), Wenzhe Ma (Author)
• Format: Book
• Published: SpringerOpen, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In this study, the potential anticancer activity and mechanism of action of SBD-2, a chalcone isolated from Shuteria involucrata, was investigated in colorectal cancer (CRC) cells. Results SBD-2 inhibited the proliferation of Caco-2 cells in a dose-dependent manner. It elicited t...