Berberine Protects against Palmitate-Induced Endothelial Dysfunction: Involvements of Upregulation of AMPK and eNOS and Downregulation of NOX4

• Main Authors: Ming Zhang (Author), Chun-Mei Wang (Author), Jing Li (Author), Zhao-Jie Meng (Author), Sheng-Nan Wei (Author), Ji Li (Author), Richard Bucala (Author), Yu-Lin Li (Author), Li Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial dysfunction is a critical factor during the initiation of cardiovascular complications in diabetes. Berberine can ameliorate endothelial dysfunction induced by diabetes. However, the underlying mechanisms remain unclear. The aim of this study was to investigate the protective effect and...