Identification of seroreactive proteins of Leptospira interrogans serovar copenhageni using a high-density protein microarray approach.

• Main Authors: Carolina Lessa-Aquino (Author), Camila Borges Rodrigues (Author), Jozelyn Pablo (Author), Rie Sasaki (Author), Algis Jasinskas (Author), Li Liang (Author), Elsio A Wunder (Author), Guilherme S Ribeiro (Author), Adam Vigil (Author), Ricardo Galler (Author), Douglas Molina (Author), Xiaowu Liang (Author), Mitermayer G Reis (Author), Albert I Ko (Author), Marco Alberto Medeiros (Author), Philip L Felgner (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leptospirosis is a widespread zoonotic disease worldwide. The lack of an adequate laboratory test is a major barrier for diagnosis, especially during the early stages of illness, when antibiotic therapy is most effective. Therefore, there is a critical need for an efficient diagnostic test for this...