Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions

• Main Authors: Stefan Bernhard (Author), Stefan Hug (Author), Alexander Elias Paul Stratmann (Author), Maike Erber (Author), Laura Vidoni (Author), Christiane Leonie Knapp (Author), Bertram Dietrich Thomaß (Author), Michael Fauler (Author), Bo Nilsson (Author), Kristina Nilsson Ekdahl (Author), Karl Föhr (Author), Christian Karl Braun (Author), Lisa Wohlgemuth (Author), Markus Huber-Lang (Author), David Alexander Christian Messerer (Author)
• Format: Book
• Published: Karger Publishers, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A sufficient response of neutrophil granulocytes stimulated by interleukin (IL)-8 is vital during systemic inflammation, for example, in sepsis or severe trauma. Moreover, IL-8 is clinically used as biomarker of inflammatory processes. However, the effects of IL-8 on cellular key regulators of neutr...