Gestational Arsenic Trioxide Exposure Acts as a Developing Neuroendocrine-Disruptor by Downregulating Nrf2/PPARγ and Upregulating Caspase-3/NF-ĸB/Cox2/BAX/iNOS/ROS

The goal of this investigation was to evaluate the effects of gestational administrations of arsenic trioxide (ATO; As 2 O 3 ) on fetal neuroendocrine development (the thyroid-cerebrum axis). Pregnant Wistar rats were orally administered ATO (5 or 10 mg/kg) from gestation day (GD) 1 to 20. Both dose...

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Hoofdauteurs: R. G. Ahmed (Auteur), A. W. El-Gareib (Auteur)
Formaat: Boek
Gepubliceerd in: SAGE Publishing, 2019-06-01T00:00:00Z.
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3rd Floor Main Library

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