Building an adaptive dose simulation framework to aid dose and schedule selection

Abstract Establishing a dosing regimen that maximizes clinical benefit and minimizes adverse effects for novel therapeutics is a key objective for drug developers. Finding an optimal dose and schedule can be particularly challenging for compounds with a narrow therapeutic window such as in oncology....

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Bibliographic Details
Main Authors: Richard Hooijmaijers (Author), Ridhi Parasrampuria (Author), Eleonora Marostica (Author), Geraldine Ferron‐Brady (Author), Teun M. Post (Author), Sandra A. G. Visser (Author)
Format: Book
Published: Wiley, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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