Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells

• Main Authors: Anthony Edwards (Author), Mara Gladstone (Author), Petros Yoon (Author), David Raben (Author), Barbara Frederick (Author), Tin Tin Su (Author)
• Format: Book
• Published: The Company of Biologists, 2011-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Combination therapy, in which two or more agents are applied, is more effective than single therapies for combating cancer. For this reason, combinations of chemotherapy with radiation are being explored in clinical trials, albeit with an empirical approach. We developed a screen to identify...