Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy

• Main Authors: Wen Li (Author), Jing Sun (Author), Xiaoxi Zhou (Author), Yue Lu (Author), Wenpeng Cui (Author), Lining Miao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pyroptosis is a recently identified type of lytic programmed cell death, in which pores form in the plasma membrane, and cells swell, rupture, and then release their contents, including inflammatory cytokines. Molecular studies indicated that pyroptosis may occur via a gasdermin D (GSDMD) and caspas...