Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer

• Main Authors: Marco Schiavone (Author), Elena Rampazzo (Author), Alessandro Casari (Author), Giusy Battilana (Author), Luca Persano (Author), Enrico Moro (Author), Shu Liu (Author), Steve D. Leach (Author), Natascia Tiso (Author), Francesco Argenton (Author)
• Format: Book
• Published: The Company of Biologists, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic adenocarcinoma, one of the worst malignancies of the exocrine pancreas, is a solid tumor with increasing incidence and mortality in industrialized countries. This condition is usually driven by oncogenic KRAS point mutations and evolves into a highly aggressive metastatic carcinoma due to...