Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice
SUMMARY A subset of patients with Parkinson's disease acquires a debilitating dementia characterized by severe cognitive impairments (i.e. Parkinson's disease dementia; PDD). Brains from PDD patients show extensive cholinergic loss as well as dopamine (DA) depletion. We used a mutant mouse...
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Main Authors: | Lilia Zurkovsky (Author), Evgeny Bychkov (Author), Elviche L. Tsakem (Author), Carley Siedlecki (Author), Randy D. Blakely (Author), Eugenia V. Gurevich (Author) |
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Format: | Book |
Published: |
The Company of Biologists,
2013-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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