Cannabinoid CB2 Receptors Modulate Microglia Function and Amyloid Dynamics in a Mouse Model of Alzheimer's Disease

• Main Authors: Samuel Ruiz de Martín Esteban (Author), Irene Benito-Cuesta (Author), Itziar Terradillos (Author), Ana M. Martínez-Relimpio (Author), M. Andrea Arnanz (Author), Gonzalo Ruiz-Pérez (Author), Claudia Korn (Author), Catarina Raposo (Author), Roman C. Sarott (Author), Matthias V. Westphal (Author), Izaskun Elezgarai (Author), Erick M. Carreira (Author), Cecilia J. Hillard (Author), Uwe Grether (Author), Pedro Grandes (Author), M. Teresa Grande (Author), Julián Romero (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The distribution and roles of the cannabinoid CB2 receptor in the CNS are still a matter of debate. Recent data suggest that, in addition to its presence in microglial cells, the CB2 receptor may be also expressed at low levels, yet biologically relevant, in other cell types such as neurons. It is a...