Dissolution enhancement of leflunomide incorporating self emulsifying drug delivery systems and liquisolid concepts

• Главные авторы: Nihal M. El-Ma (Автор), Alia Badawi (Автор), Mohammed Effat Abdullah (Автор), Nevine Shawky Abdelmalak (Автор)
• Формат: ‌
• Опубликовано: Faculty of Pharmacy, Cairo University, 2017-06-01T00:00:00Z.
• Предметы: article
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The objective of this study is to enhance the dissolution properties of leflunomide, a class BCS-II drug by incorporating the self emulsifying (SE) form of the drug onto liquisolid systems in the form of tablets. Different formulae were prepared by dissolving leflunomide in PEG300 then forming SE sy...