Pharmacokinetics of a liposomal formulation of doxorubicin in rats

• Main Authors: Zongyu Liu (Author), Ye Bi (Author), Yating Sun (Author), Fei Hao (Author), Jiahui Lu (Author), Qingfan Meng (Author), Robert J. Lee (Author), Yaping Tian (Author), Jing Xie (Author)
• Format: Book
• Published: Elsevier, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Measuring free drug concentration following systemic administration of a liposomal drug is a crucial aspect of the assessment of its in vivo behavior. Therefore we require an efficient method to separate free drug in the plasma from encapsulated drug. Objectives: To study the pharmacokin...