The Gasotransmitter Hydrogen Sulfide (H₂S) Prevents Pathologic Calcification (PC) in Cartilage

• Main Authors: Sonia Nasi (Author), Driss Ehirchiou (Author), Jessica Bertrand (Author), Mariela Castelblanco (Author), James Mitchell (Author), Isao Ishii (Author), Alexander So (Author), Nathalie Busso (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pathologic calcification (PC) is a painful and disabling condition whereby calcium-containing crystals deposit in tissues that do not physiologically calcify: cartilage, tendons, muscle, vessels and skin. In cartilage, compression and inflammation triggered by PC leads to cartilage degradation typic...