Experimental study of the pharmacokinetics of rifabutin in liposomal form

• Main Authors: M. V. Carlin (Author), V. M. Cosman (Author), O. N. Pozharitskaya (Author), A. N. Shikov (Author), M. N. Makarova (Author), V. G. Makarov (Author), V. Y. Balabanyan (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

On mongrel male rats studied pharmacokinetics of rifabutin in liposomal form, the relative bioavailability and tissue distribution after intratracheal administration, evaluated pharmacokinetic linearity. To determine rifabutin in plasma and organs were developed and validated HPLC method with UV det...