Recent advances on development of p21-activated kinase 4 inhibitors as anti-tumor agents

The p21-activated kinase 4 (PAK4) is a member of the PAKs family. It is overexpressed in multiple tumor tissues. Pharmacological inhibition of PAK4 attenuates proliferation, migration, and invasion of cancer cells. Recent studies revealed that inhibition of PAK4 sensitizes immunotherapy which has be...

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Main Authors: Yang Li (Author), Qing Lu (Author), Chenghu Xie (Author), Yiming Yu (Author), Ao Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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