Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites

• Autori principali: Mari L. Lund (Autore), Kristoffer L. Egerod (Autore), Maja S. Engelstoft (Autore), Oksana Dmytriyeva (Autore), Elvar Theodorsson (Autore), Bhavik A. Patel (Autore), Thue W. Schwartz (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2018-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Objectives: 5-HT storing enterochromaffin (EC) cells are believed to respond to nutrient and gut microbial components, and 5-HT receptor-expressing afferent vagal neurons have been described to be the major sensors of nutrients in the GI-tract. However, the molecular mechanism through which EC cells...