Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks

• Main Authors: Shunheng Zhou (Author), Yu-e Huang (Author), Haizhou Liu (Author), Xu Zhou (Author), Mengqin Yuan (Author), Fei Hou (Author), Lihong Wang (Author), Wei Jiang (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high intratumoral heterogeneity. Recent studies revealed that TNBC patients might comprise cells with distinct molecular subtypes. In addition, gene regulatory networks (GRNs) constructed based on single-cell RNA sequencing (scR...