Activation of TGR5 Increases Urine Concentration by Inducing AQP2 and AQP3 Expression in Renal Medullary Collecting Ducts

• Main Authors: Yanlin Guo (Author), Rongfang Qiao (Author), Guixiang Xie (Author), Yao Yao (Author), Chunxiu Du (Author), Yunxia Shao (Author), Youfei Guan (Author), Xiaoyan Zhang (Author)
• Format: Book
• Published: Karger Publishers, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: G protein-coupled bile acid receptor (TGR5), the first G protein-coupled receptor for bile acids identified, is capable of activating a variety of intracellular signaling pathways after interacting with bile acids. TGR5 plays an important role in multiple physiological processes and is...