pH-Responsive Liposomes of Dioleoyl Phosphatidylethanolamine and Cholesteryl Hemisuccinate for the Enhanced Anticancer Efficacy of Cisplatin

• Main Authors: Hassan Shah (Author), Asadullah Madni (Author), Muhammad Muzamil Khan (Author), Fiaz- (Author), Nasrullah Jan (Author), Safiullah Khan (Author), Muhammad Abdur Rahim (Author), Shahzeb Khan (Author), Meser M. Ali (Author), Mohsin Kazi (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current study aimed to develop pH-responsive cisplatin-loaded liposomes (CDDP@PLs) via the thin film hydration method. Formulations with varied ratios of dioleoyl phosphatidylethanolamine (DOPE) to cholesteryl hemisuccinate (CHEMS) were investigated to obtain the optimal particle size, zeta pote...