Evading Doxorubicin-Induced Systemic Immunosuppression Using Ultrasound-Responsive Liposomes Combined with Focused Ultrasound

• Main Authors: Jeongjin Lee (Author), Wooram Um (Author), Hyungwon Moon (Author), Hyeyeon Joo (Author), Yeari Song (Author), Minsung Park (Author), Been Yoon (Author), Hyun-Ryoung Kim (Author), Jae Hyung Park (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin (DOX) is a representative anticancer drug with a unique ability to induce immunogenic cell death of cancer cells. However, undesired toxicity on immune cells has remained a significant challenge, hindering the usage of DOX in cancer immunotherapy. Here, we report a combined therapy to av...