Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells

• Main Authors: Fen Hu (Author), Yuxi Sun (Author), Yunfeng Zhang (Author), Jiaxin Chen (Author), Yingzi Deng (Author), Yifei Li (Author), Ruobing Li (Author), Juan Zhang (Author), Yongping Liang (Author), Yan Liu (Author), Shuqing Wang (Author), Mi Li (Author), Lina Zhao (Author), Yuwei Liu (Author), Xiaodong Gong (Author), Haifeng Cai (Author), Shouqin Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostate cancer has the second highest incidence among male malignancies. Only a few studies exist on the inhibitory effects of maslinic acid (MA) on prostate cancer. Herein we found that MA inhibits prostate cancer cell proliferation by decreasing CDK2, CDK4, and CDK6 expression and concurrently in...