Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model

• Main Authors: Jiye Chen (Author), Yongjian Zhang (Author), Yongcheng Wang (Author), Ping Jiang (Author), Guofeng Zhou (Author), Zhaoyu Li (Author), Jinlong Yang (Author), Xiao Li (Author)
• Format: Book
• Published: BMC, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Guizhi decoction (GZD), a classical Chinese herbal formula, has been widely used to treat hypertension, but its underlying mechanisms remain elusive. The present study aimed to explore the potential mechanisms and therapeutic effects of GZD on hypertension by integrating network...