Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas

• Main Authors: Odessica Hughes (Author), Amy R. Bentley (Author), Charles E. Breeze (Author), Francois Aguet (Author), Xiaoguang Xu (Author), Girish Nadkarni (Author), Quan Sun (Author), Bridget M. Lin (Author), Thomas Gilliland (Author), Mariah C. Meyer (Author), Jiawen Du (Author), Laura M. Raffield (Author), Holly Kramer (Author), Robert W. Morton (Author), Mateus H. Gouveia (Author), Elizabeth G. Atkinson (Author), Adan Valladares-Salgado (Author), Niels Wacher-Rodarte (Author), Nicole D. Dueker (Author), Xiuqing Guo (Author), Yang Hai (Author), Adebowale Adeyemo (Author), Lyle G. Best (Author), Jianwen Cai (Author), Guanjie Chen (Author), Michael Chong (Author), Ayo Doumatey (Author), James Eales (Author), Mark O. Goodarzi (Author), Eli Ipp (Author), Marguerite Ryan Irvin (Author), Minzhi Jiang (Author), Alana C. Jones (Author), Charles Kooperberg (Author), Jose E. Krieger (Author), Ethan M. Lange (Author), Matthew B. Lanktree (Author), James P. Lash (Author), Paulo A. Lotufo (Author), Ruth J.F. Loos (Author), Vy Thi Ha My (Author), Jesús Peralta-Romero (Author), Lihong Qi (Author), Leslie J. Raffel (Author), Stephen S. Rich (Author), Erik J. Rodriquez (Author), Eduardo Tarazona-Santos (Author), Kent D. Taylor (Author), Jason G. Umans (Author), Jia Wen (Author), Bessie A. Young (Author), Zhi Yu (Author), Ying Zhang (Author), Yii-Der Ida Chen (Author), Tanja Rundek (Author), Jerome I. Rotter (Author), Miguel Cruz (Author), Myriam Fornage (Author), Maria Fernanda Lima-Costa (Author), Alexandre C. Pereira (Author), Guillaume Paré (Author), Pradeep Natarajan (Author), Shelley A. Cole (Author), April P. Carson (Author), Leslie A. Lange (Author), Yun Li (Author), Eliseo J. Perez-Stable (Author), Ron Do (Author), Fadi J. Charchar (Author), Maciej Tomaszewski (Author), Josyf C. Mychaleckyj (Author), Charles Rotimi (Author), Andrew P. Morris (Author), Nora Franceschini (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Chronic kidney disease is a leading cause of death and disability globally and impacts individuals of African ancestry (AFR) or with ancestry in the Americas (AMS) who are under-represented in genome-wide association studies (GWASs) of kidney function. To address this bias, we conducted a l...