Regulatory drugs of glutamate transporter 1 (EAAT2/GLT-1) expression and activity: role in quenching oxidative damage

• Main Authors: Davinia Domínguez-González (Author), Blanca Romero-Llopis (Author), Marta Roldán-Lázaro (Author), Lorena Baquero (Author), Rita Noverques (Author), Federico V Pallardó (Author), Juan Antonio Navarro (Author), Pilar Gonzalez-Cabo (Author)
• Format: Book
• Published: Bioscientifica, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

l-glutamate is one of the major neurotransmitters in the central nervous system, directly and indirectly involved in numerous brain functions. In several neurodegenerative diseases, it has been observed that an excess of extracellular glutamate overstimulates glutamate receptors, leading to exacerba...