Combined Machine Learning and GRID-Independent Molecular Descriptor (GRIND) Models to Probe the Activity Profiles of 5-Lipoxygenase Activating Protein Inhibitors

Leukotrienes (LTs) are pro-inflammatory lipid mediators derived from arachidonic acid (AA), and their high production has been reported in multiple allergic, autoimmune, and cardiovascular disorders. The biological synthesis of leukotrienes is instigated by transfer of AA to 5-lipoxygenase (5-LO) vi...

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Huvudskapare: Hafiza Aliza Khan (Författare, medförfattare), Ishrat Jabeen (Författare, medförfattare)
Materialtyp: Bok
Publicerad: Frontiers Media S.A., 2022-03-01T00:00:00Z.
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