Increased Krüppel-like factor 12 in recurrent implantation failure impairs endometrial decidualization by repressing Nur77 expression

• Hauptverfasser: Chenyang Huang (Verfasst von), Yue Jiang (Verfasst von), Jianjun Zhou (Verfasst von), Qiang Yan (Verfasst von), Ruiwei Jiang (Verfasst von), Xi Cheng (Verfasst von), Jun Xing (Verfasst von), Lijun Ding (Verfasst von), Jianxin Sun (Verfasst von), Guijun Yan (Verfasst von), Haixiang Sun (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2017-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Decidualization is a prerequisite for successful implantation and the establishment of pregnancy. A critical role of impaired decidualization in subfertility has been established. In human endometrial stromal cells (hESCs), Krüppel-like factor 12 (KLF12) and Nur77 are novel regu...