Summary of single nucleotide polymorphisms in filaggrin associated with atopic dermatitis

• Main Authors: Rachita Pandya (Author), Mohsen Baghchechi (Author), Sinead Langan (Author), David J. Margolis (Author), Lavinia Paternoster (Author), Cathryn Sibbald (Author), Joy Wan (Author), Saman Zaman (Author), Katrina Abuabara (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Loss of function mutations in the filaggrin gene (FLG) play an important role in the pathogenesis of atopic dermatitis (AD). However, FLG is structurally challenging to sequence using conventional high‐throughput techniques. Genome‐wide association studies (GWAS) chips and imputa...