Utilization of Knockout Mice to Examine the Potential Role of Gastric Histamine H2-Receptors in Menetrier's Disease

• Những tác giả chính: Toshiki Ogawa (Tác giả), Kazuhiko Maeda (Tác giả), Shunsuke Tonai (Tác giả), Takashi Kobayashi (Tác giả), Takeshi Watanabe (Tác giả), Susumu Okabe (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2003-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Menetrier's disease is characterized by giant gastric folds with foveolar hyperplasia and cystic dilatation, hypoproteinemia, and enhanced mucus secretion. The etiology remains unresolved and an effective treatment has yet to be established. Here we show that histamine H2-receptor deficient mic...