Semisolid Wet Sol-Gel Silica/Hydroxypropyl Methyl Cellulose Formulation for Slow Release of Serpin B3 Promotes Wound Healing In Vivo

• Main Authors: Mattia Albiero (Author), Alice Fullin (Author), Gianmarco Villano (Author), Alessandra Biasiolo (Author), Santina Quarta (Author), Simone Bernardotto (Author), Cristian Turato (Author), Mariagrazia Ruvoletto (Author), Gian Paolo Fadini (Author), Patrizia Pontisso (Author), Margherita Morpurgo (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Foot ulcerations are a disabling complication of diabetes and no treatment is currently available based on disease mechanisms. The protein serpin B3 (SB3) was identified as a positive biomarker of successful diabetic wound healing; therefore, its exogenous administration may promote healing. The top...