Safety and immunogenicity of an adjuvanted Escherichia coli adhesin vaccine in healthy women with and without histories of recurrent urinary tract infections: results from a first-in-human phase 1 study

• Main Authors: Gary R. Eldridge (Author), Heidi Hughey (Author), Lois Rosenberger (Author), Steven M. Martin (Author), Andrew Marc Shapiro (Author), Elizabeth D'Antonio (Author), Kent G. Krejci (Author), Neal Shore (Author), James Peterson (Author), Andrea S. Lukes (Author), Courtney M. Starks (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide a potential solution to these problems. This study focused on development of an investigational vaccine to prevent...