Inhibition of the TNF-α-Induced Serine Phosphorylation of IRS-1 at 636/639 by AICAR
AMP-activated protein kinase (AMPK) contributes to the acceleration of insulin signaling. However, the mechanism by which AMPK regulates insulin signaling remains unclear. Serine phosphorylation of insulin receptor substrate (IRS)-1 negatively regulates insulin signaling. Here we investigated the ro...
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Main Authors: | Tomohito Shibata (Author), Akira Takaguri (Author), Kazuo Ichihara (Author), Kumi Satoh (Author) |
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Format: | Book |
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Elsevier,
2013-01-01T00:00:00Z.
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