Inhibition of the TNF-α-Induced Serine Phosphorylation of IRS-1 at 636/639 by AICAR

AMP-activated protein kinase (AMPK) contributes to the acceleration of insulin signaling. However, the mechanism by which AMPK regulates insulin signaling remains unclear. Serine phosphorylation of insulin receptor substrate (IRS)-1 negatively regulates insulin signaling. Here we investigated the ro...

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Main Authors: Tomohito Shibata (Author), Akira Takaguri (Author), Kazuo Ichihara (Author), Kumi Satoh (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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