The Inflammatory Response Induced by Aspergillus fumigatus Conidia Is Dependent on Complement Activation: Insight from a Whole Blood Model

• Hoofdauteurs: Beatrice Fageräng (Auteur), Maximilian Peter Götz (Auteur), Leon Cyranka (Auteur), Corinna Lau (Auteur), Per H. Nilsson (Auteur), Tom Eirik Mollnes (Auteur), Peter Garred (Auteur)
• Formaat: Boek
• Gepubliceerd in: Karger Publishers, 2024-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: We aimed to elucidate the inflammatory response of Aspergillus fumigatus conidia in a whole-blood model of innate immune activation and to compare it with the well-characterized inflammatory reaction to Escherichia coli. Methods: Employing a human lepirudin whole-blood model, we analyz...