The Inflammatory Response Induced by Aspergillus fumigatus Conidia Is Dependent on Complement Activation: Insight from a Whole Blood Model

• Main Authors: Beatrice Fageräng (Author), Maximilian Peter Götz (Author), Leon Cyranka (Author), Corinna Lau (Author), Per H. Nilsson (Author), Tom Eirik Mollnes (Author), Peter Garred (Author)
• Format: Book
• Published: Karger Publishers, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: We aimed to elucidate the inflammatory response of Aspergillus fumigatus conidia in a whole-blood model of innate immune activation and to compare it with the well-characterized inflammatory reaction to Escherichia coli. Methods: Employing a human lepirudin whole-blood model, we analyz...