A Palmitoylethanolamide Producing Lactobacillus paracasei Improves Clostridium difficile Toxin A-Induced Colitis

• Main Authors: Giuseppe Esposito (Author), Chiara Corpetti (Author), Marcella Pesce (Author), Luisa Seguella (Author), Giuseppe Annunziata (Author), Alessandro Del Re (Author), Martina Vincenzi (Author), Roberta Lattanzi (Author), Jie Lu (Author), Walter Sanseverino (Author), Giovanni Sarnelli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genetically engineered probiotics, able to in situ deliver therapeutically active compounds while restoring gut eubiosis, could represent an attractive therapeutic alternative in Clostridium difficile infection (CDI). Palmitoylethanolamide is an endogenous lipid able to exert immunomodulatory activi...