Glioma-Associated Sialoglycans Drive the Immune Suppressive Phenotype and Function of Myeloid Cells

• Main Authors: Lenneke A. M. Cornelissen (Author), Kim C. M. Santegoets (Author), Esther D. Kers-Rebel (Author), Sandra A. J. F. H. Bossmann (Author), Mark Ter Laan (Author), Daniel Granado (Author), Gosse J. Adema (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tumor microenvironment of glioblastoma IDH-wildtype is highly immune suppressive and is characterized by a strong component of myeloid-derived suppressor cells (MDSCs). To interfere with the immune suppressive functions of MDSCs, a comprehensive understanding on how MDSCs acquire their suppressi...