A cytoplasmic new catalytic subunit of calcineurin in Trypanosoma cruzi and its molecular and functional characterization.

• Main Authors: Patricio R Orrego (Author), Héctor Olivares (Author), Esteban M Cordero (Author), Albert Bressan (Author), Mauro Cortez (Author), Hernán Sagua (Author), Ivan Neira (Author), Jorge González (Author), José Franco da Silveira (Author), Nobuko Yoshida (Author), Jorge E Araya (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasitological cure for Chagas disease is considered extremely difficult to achieve because of the lack of effective chemotherapeutic agents against Trypanosoma cruzi at different stages of infection. There are currently only two drugs available. These have several limitations and can produce serio...