Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

• Main Authors: Kathleen G. Mountjoy (Author), Alexandre Caron (Author), Kristina Hubbard (Author), Avik Shome (Author), Angus C. Grey (Author), Bo Sun (Author), Sarah Bould (Author), Martin Middleditch (Author), Beau Pontré (Author), Ailsa McGregor (Author), Paul W.R. Harris (Author), Renata Kowalczyk (Author), Margaret A. Brimble (Author), Rikus Botha (Author), Karen M.L. Tan (Author), Sarah J. Piper (Author), Christina Buchanan (Author), Syann Lee (Author), Anthony P. Coll (Author), Joel K. Elmquist (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Regulation of energy balance depends on pro-opiomelanocortin (POMC)-derived peptides and melanocortin-4 receptor (MC4R). Alpha-melanocyte stimulating hormone (α-MSH) is the predicted natural POMC-derived peptide that regulates energy balance. Desacetyl-α-MSH, the precursor for α-MSH, is p...