Pathophysiological Response to Hypoxia - From the Molecular Mechanisms of Malady to Drug Discovery: Inflammatory Responses of Hypoxia-Inducible Factor 1α (HIF-1α) in T Cells Observed in Development of Vascular Remodeling

• Autors principals: Shuhei Tomita (Autor), Yoshitaka Kihira (Autor), Masaki Imanishi (Autor), Yayoi Fukuhara (Autor), Yuko Imamura (Autor), Keisuke Ishizawa (Autor), Yasumasa Ikeda (Autor), Koichiro Tsuchiya (Autor), Toshiaki Tamaki (Autor)
• Format: Llibre
• Publicat: Elsevier, 2011-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Recent studies have shown that the cellular immune response to the hypoxic microenvironment constructed by vascular remodeling development modulates the resulting pathologic alterations. A major mechanism mediating adaptive responses to reduced oxygen availability is the regulation of transcription...