Intrathecal gastrodin alleviates allodynia in a rat spinal nerve ligation model through NLRP3 inflammasome inhibition

• Main Authors: JunXiu Jin (Author), Dong Ho Kang (Author), Geon Hui Lee (Author), Woong Mo Kim (Author), Jeong Il Choi (Author)
• 格式: 图书
• 出版: BMC, 2024-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Gastrodin (GAS), a main bioactive component of the herbal plant, Gastrodia elata Blume, has shown to have beneficial effects on neuroinflammatory diseases such as Alzheimer's disease in animal studies and migraine in clinical studies. Inflammasome is a multimeric protein com...