Three-Component Synthesis of 2-Amino-3-cyano-4<i>H</i>-chromenes, In Silico Analysis of Their Pharmacological Profile, and In Vitro Anticancer and Antifungal Testing

• Main Authors: Alberto Feliciano (Author), Omar Gómez-García (Author), Carlos H. Escalante (Author), Mario A. Rodríguez-Hernández (Author), Mariana Vargas-Fuentes (Author), Dulce Andrade-Pavón (Author), Lourdes Villa-Tanaca (Author), Cecilio Álvarez-Toledano (Author), María Teresa Ramírez-Apan (Author), Miguel A. Vázquez (Author), Joaquín Tamariz (Author), Francisco Delgado (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chromenes are compounds that may be useful for inhibiting topoisomerase and cytochrome, enzymes involved in the growth of cancer and fungal cells, respectively. The aim of this study was to synthesize a series of some novel 2-amino-3-cyano-4-aryl-6,7-methylendioxy-4<i>H</i>-chromenes <...