pH-Responsive Nanoparticles for Delivery of Paclitaxel to the Injury Site for Inhibiting Vascular Restenosis

• Главные авторы: Huiru Zhu (Автор), Li Kong (Автор), Xu Zhu (Автор), Tingting Ran (Автор), Xiaojuan Ji (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-02-01T00:00:00Z.
• Предметы: article
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A high incidence of restenosis has been reported at the site of inflammation following angioplasty and stent implantation. The anti-proliferative drug paclitaxel (PTX) could help to reduce inflammation and restenosis; however, it has poor water solubility and serious adverse side effects at high dos...