Spironolactone Induces Vasodilation by Endothelium-Dependent Mechanisms Involving NO and by Endothelium-Independent Mechanisms Blocking Ca<sup>2+</sup> Channels

Background: Spironolactone (SPI) is a diuretic widely used to treat cardiovascular diseases (CVD) and is non-specific for mineralocorticoid receptors (MR) and with an affinity for progesterone (PR) and androgen (AR) receptors. Since 2009, it has been suggested that pharmaceuticals are emerging conta...

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Main Authors: Margarida Lorigo (Author), João Amaro (Author), Elisa Cairrao (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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