Neuronal Excitation Induces Tau Protein Dephosphorylation via Protein Phosphatase 1 Activation to Promote Its Binding with Stable Microtubules

• Auteurs principaux: Sosuke Yagishita (Auteur), Megumi Shibata (Auteur), Akiko Furuno (Auteur), Shuji Wakatsuki (Auteur), Toshiyuki Araki (Auteur)
• Format: Livre
• Publié: MDPI AG, 2024-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The tau protein is a microtubule-associated protein that promotes microtubule stabilization. The phosphorylation of the tau protein has been linked to its dissociation from microtubules. Here, we examined the relationship between neuronal depolarization activity and tau protein phosphorylation by em...