Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2

Human tryptophan hydroxylase 2 (TPH2) is the rate-limiting enzyme in the synthesis of serotonin. Its dysfunction has been implicated in various psychiatric disorders such as depression, autism, and bipolar disorder. TPH2 is typically decreased in stability and catalytic activity in patients; thus, s...

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Main Authors: Kongfu Zhu (Author), Chao Liu (Author), Yuanzhu Gao (Author), Jianping Lu (Author), Daping Wang (Author), Huawei Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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