Response of the Glutathione (GSH) Antioxidant Defense System to Oxidative Injury in Necrotizing Enterocolitis

• Main Authors: Alena Golubkova (Author), Tyler Leiva (Author), Katherine Snyder (Author), Camille Schlegel (Author), Sarah M. Bonvicino (Author), Martin-Paul Agbaga (Author), Richard S. Brush (Author), Jason M. Hansen (Author), Peter F. Vitiello (Author), Catherine J. Hunter (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Necrotizing enterocolitis (NEC) is a neonatal intestinal disease associated with oxidative stress. The targets of peroxidation and the role of the innate intestinal epithelial antioxidant defense system are ill-defined. We hypothesized that oxidative stress in NEC correlates with oxidized GSH redox...