No association between polymorphisms in the <it>BDNF </it>gene and age at onset in Huntington disease

• Main Authors: Kraus Peter H (Author), Andrich Jürgen (Author), Saft Carsten (Author), Wieczorek Stefan (Author), Akkad Amer D (Author), Mai Maren (Author), Epplen Jörg T (Author), Arning Larissa (Author)
• Format: Book
• Published: BMC, 2006-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Recent evidence suggests that brain-derived neurotrophic factor (BDNF) is an attractive candidate for modifying age at onset (AO) in Huntington disease (HD). In particular, the functional Val66Met polymorphism appeared to exert a sig...