Synthesis, diuretic activity research and QSAR-analysis of N-(1,3,4-tiadiazol-2-il)substituted amides of alkanecarboxylic acids

• প্রধান লেখক: І. V. Drapak (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: The State Expert Center of the Ministry of Health of Ukraine, 2019-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Diuretics are effective drugs that are widely used in medicine, but have unwanted side effects. The derivative of thiadiazole - acetozolamide is a known diuretic. Therefore, the search for diuretics in this series and the establishment of quantitative «structure-activity» (QSAR) dependencies is appr...