Short-Term Regulation of FcγR-Mediated Phagocytosis by TLRs in Macrophages: Participation of 5-Lipoxygenase Products

• Main Authors: Carla da S. Pinheiro (Author), Ana Paula T. Monteiro (Author), Fabiano F. Dutra (Author), Marcelo T. Bozza (Author), Marc Peters-Golden (Author), Claudia F. Benjamim (Author), Claudio Canetti (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, increase FcγR-mediated phagocytosis. Here, we evalu...